DCLRE1B Polyclonal AntibodyE-AB-33334
Product Type: Antibody
Descritpion: DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links.DCLRE1B (DNA Cross-Link Repair 1B) is a Protein Coding gene. Diseases associated with DCLRE1B include Fanconi Anemia, Complementation Group A and Dyskeratosis Congenita. Among its related pathways are Fanconi anemia pathway and DNA Double-Strand Break Repair. GO annotations related to this gene include 5-3 exonuclease activity. An important paralog of this gene is DCLRE1C.
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:40000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human SNM1B.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 60kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoskeleton,centrosome,Nucleus,nuclear body,nuclear chromosome, telomeric region,nucleoplasm,Other locations:chromosome, telomeric region,cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-dclre1b_polyclonal_antibody-29659.html
Manual Link: https://www.elabscience.com/viewpdf-29659-elabscience-E-AB-33334.PDF