GABAA Receptor epsilon Polyclonal AntibodyE-AB-33338
Product Type: Antibody
Descritpion: The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.GABRE (Gamma-Aminobutyric Acid Type A Receptor Epsilon Subunit) is a Protein Coding gene. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include chloride channel activity and GABA-A receptor activity. An important paralog of this gene is GABRG3.
Research Areas: Cancer, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human GABAA rangle: R?.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 58kDa
Tissue Specificity/Positive Control: Expressed in many tissues. Highest levels of expression in adult heart and placenta.
Cellular Localization: Cell junction>synapse>postsynaptic cell membrane. Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-gabaa_receptor_epsilon_polyclonal_antibody-29663.html
Manual Link: https://www.elabscience.com/viewpdf-29663-elabscience-E-AB-33338.PDF