UBE4A Polyclonal Antibody
UBE4A Polyclonal Antibody

UBE4A Polyclonal Antibody

E-AB-33350

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 
Research Areas: Cell Biology, Epigenetics and Nuclear Signaling
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:10000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: Q14139
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the N-terminal region of human UBE4A.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 123kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus,Other locations:cytoplasm,ubiquitin ligase complex
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-ube4a_polyclonal_antibody-29675.html
Manual Link: https://www.elabscience.com/viewpdf-29675-elabscience-E-AB-33350.PDF