HNF1B Polyclonal AntibodyE-AB-33353
Product Type: Antibody
Descritpion: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human HNF-1?.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 61kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-hnf1b_polyclonal_antibody-29678.html
Manual Link: https://www.elabscience.com/viewpdf-29678-elabscience-E-AB-33353.PDF