NF?B-p105 Polyclonal Antibody
NF?B-p105 Polyclonal Antibody

NF?B-p105 Polyclonal Antibody

E-AB-33379

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P19838
Gene Accession:
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human NF?B-p105 around the non-phosphorylation site of Ser903.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 105kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-nf?b_p105_polyclonal_antibody-29704.html
Manual Link: https://www.elabscience.com/viewpdf-29704-elabscience-E-AB-33379.PDF