APLN Polyclonal Antibody
APLN Polyclonal Antibody

APLN Polyclonal Antibody

E-AB-33433

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. APLN (Apelin) is a Protein Coding gene. Diseases associated with APLN include Syndrome Of Inappropriate Antidiuretic Hormone and Severe Pre-Eclampsia. Among its related pathways are Peptide ligand-binding receptors and Apelin signaling pathway. GO annotations related to this gene include receptor binding and G-protein coupled receptor binding.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: Q9ULZ1
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the C-terminal region of human Apelin.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 9kDa
Tissue Specificity/Positive Control: Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-apln_polyclonal_antibody-29758.html
Manual Link: https://www.elabscience.com/viewpdf-29758-elabscience-E-AB-33433.PDF