F3 Polyclonal Antibody
F3 Polyclonal Antibody

F3 Polyclonal Antibody

E-AB-33464

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Research Areas: Cancer, Cardiovascular
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P13726
Gene Accession:
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human TF.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 33kDa
Tissue Specificity/Positive Control: Lung, placenta and pancreas.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-f3_polyclonal_antibody-29789.html
Manual Link: https://www.elabscience.com/viewpdf-29789-elabscience-E-AB-33464.PDF