Product Type: Antibody
Descritpion: Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.
Research Areas: Cancer, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human Calbindin D28K.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 30kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosol,Extracellular region or secreted,extracellular exosome,Nucleus,Other locations:axon,dendrite,dendritic spine,neuronal cell body,synapse,terminal bouton
Storage: Store at -20C. Avoid freeze / thaw cycles.