SPTLC1 Polyclonal Antibody
SPTLC1 Polyclonal Antibody

SPTLC1 Polyclonal Antibody

E-AB-33502

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: O15269
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the C-terminal region of human SPTLC1.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 52kDa
Tissue Specificity/Positive Control: Widely expressed. Not detected in small intestine.
Cellular Localization: Endoplasmic reticulum membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-sptlc1_polyclonal_antibody-29827.html
Manual Link: https://www.elabscience.com/viewpdf-29827-elabscience-E-AB-33502.PDF