MACC1 Polyclonal AntibodyE-AB-33562
Product Type: Antibody
Descritpion: MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human MACC1.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 97kDa
Tissue Specificity/Positive Control: Preferentially expressed in metastasizing tumors.
Cellular Localization: Cytoplasm. Nucleus. Mainly found in the cytoplasm in non-metastasizing tumors.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-macc1_polyclonal_antibody-29887.html
Manual Link: https://www.elabscience.com/viewpdf-29887-elabscience-E-AB-33562.PDF