Product Type: Antibody
Descritpion: INHBE encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. Inhibins have been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. This gene may be upregulated under conditions of endoplasmic reticulum stress, and this protein may inhibit cellular proliferation and growth in pancreas and liver. INHBE (Inhibin Beta E Subunit) is a Protein Coding gene. Among its related pathways are TGF-beta signaling pathway (KEGG) and Signaling pathways regulating pluripotency of stem cells. GO annotations related to this gene include cytokine activity and hormone activity. An important paralog of this gene is INHBC.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human Inhibin ?-E.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 39kDa
Tissue Specificity/Positive Control:
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.