Product Type: Antibody
Descritpion: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).IFNL2 (Interferon Lambda 2) is a Protein Coding gene. Among its related pathways are all-trans-Retinoic Acid Mediated Apoptosis and Innate Immune System. GO annotations related to this gene include receptor binding and cytokine activity. An important paralog of this gene is IFNL3.
Research Areas: Immunology
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human IL-28.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 22kDa
Tissue Specificity/Positive Control:
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.