Product Type: Antibody
Descritpion: May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Microbiology
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human Amphiphysin II.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 65kDa
Tissue Specificity/Positive Control: Ubiquitous. Highest expression in the brain and muscle. Isoform IIA is expressed only in the brain where it is concentrated in axon initial segments and nodes of Ranvier. Isoform BIN1 is widely expressed with highest expression in skeletal muscle.
Cellular Localization: Cytoplasm and Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.