Product Type: Antibody
Descritpion: This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Immunology, Stem cells
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000-1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human CD6.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 72kDa
Tissue Specificity/Positive Control: Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.