NECTIN1 Polyclonal Antibody
NECTIN1 Polyclonal Antibody

NECTIN1 Polyclonal Antibody

E-AB-33679

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Research Areas: Cancer, Microbiology, Neuroscience
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: Q15223
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human Nectin 1.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 57kDa
Tissue Specificity/Positive Control:
Cellular Localization: Secreted and Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-nectin1_polyclonal_antibody-30004.html
Manual Link: https://www.elabscience.com/viewpdf-30004-elabscience-E-AB-33679.PDF