CD240d Polyclonal AntibodyE-AB-33703
Product Type: Antibody
Descritpion: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. RHD (Rh Blood Group D Antigen) is a Protein Coding gene. Diseases associated with RHD include Anemia, Hemolytic, Rh-Null, Regulator Type and Skeletal Muscle Cancer. GO annotations related to this gene include ammonium transmembrane transporter activity. An important paralog of this gene is RHCE.
Research Areas: Cardiovascular, Immunology
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human CD240d.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 45kDa
Tissue Specificity/Positive Control: Restricted to tissues or cell lines expressing erythroid characters.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cd240d_polyclonal_antibody-30028.html
Manual Link: https://www.elabscience.com/viewpdf-30028-elabscience-E-AB-33703.PDF