CD192 Polyclonal AntibodyE-AB-33712
Product Type: Antibody
Descritpion: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Research Areas: Cancer, Cardiovascular, Immunology, Microbiology, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human CD192.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 42kDa
Tissue Specificity/Positive Control: Expressed by monocytes and IL2-activated NK cells.
Cellular Localization: Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cd192_polyclonal_antibody-30037.html
Manual Link: https://www.elabscience.com/viewpdf-30037-elabscience-E-AB-33712.PDF