BTC Polyclonal AntibodyE-AB-33719
Product Type: Antibody
Descritpion: This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Probetacellulin.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 20kDa
Tissue Specificity/Positive Control: Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
Cellular Localization: Cell membrane and Secreted>extracellular space.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-btc_polyclonal_antibody-30044.html
Manual Link: https://www.elabscience.com/viewpdf-30044-elabscience-E-AB-33719.PDF