MAP1LC3B Polyclonal Antibody
MAP1LC3B Polyclonal Antibody

MAP1LC3B Polyclonal Antibody

E-AB-33747

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Applications: WB,IHC-p,IF
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300
Size: 200 uL
Concentration: 1mg/mL
Swissprot: Q9GZQ8
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant Protein
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.
Cellular Localization: Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-map1lc3b_polyclonal_antibody-41156.html
Manual Link: https://www.elabscience.com/viewpdf-41156-elabscience-E-AB-33747.PDF