Product Type: Antibody
Descritpion: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53.
Research Areas: Cancer, Cardiovascular
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:40000
Size: 200 uL
Immunogen: Synthetic Peptide
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Purification: Affinity purification
Tissue Specificity/Positive Control: Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes.
Cellular Localization: Cell membrane. Likely to be concentrated at cell-cell adhesion sites.
Storage: Store at -20C. Avoid freeze / thaw cycles.