Product Type: Antibody
Descritpion: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
Research Areas: Cancer, Neuroscience
Recommended Dilutions: WB 1:1000-2000, IHC 1:100-200
Size: 200 uL
Immunogen: Synthetic Peptide
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Tissue Specificity/Positive Control: Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.
Cellular Localization: Plasma membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.