Di-Methyl-Histone H3 (Lys80) Polyclonal AntibodyE-AB-50002
Product Category: Phospho/Acetyl/Methyl
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000
Gene ID: 8350
Immunogen: Synthesized Tri-Methyl peptide derived from human Histone H3
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nuclear chromosome,nuclear chromosome, telomeric region,nuclear nucleosome,nucleoplasm,nucleus,Other locations:nucleosome,protein complex
Product Link: https://www.elabscience.com/p-di_methyl_histone_h3_(lys80)_polyclonal_antibody-41333.html
Manaul Link: https://www.elabscience.com/viewpdf-41333-elabscience-E-AB-50002.PDF