Phospho-MERTK/TYRO3 (Tyr753/Tyr685) Polyclonal Antibody

Phospho-MERTK/TYRO3 (Tyr753/Tyr685) Polyclonal Antibody

E-AB-51041

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a Protein Coding gene. Diseases associated with MERTK include Retinitis Pigmentosa 38 and Mertk-Related Retinitis Pigmentosa. Among its related pathways are GPCR Pathway and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AXL.
TYRO3 (TYRO3 Protein Tyrosine Kinase) is a Protein Coding gene. Diseases associated with TYRO3 include External Ear Carcinoma and Lymphocytic Choriomeningitis. Among its related pathways are GPCR Pathway and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AXL.
Research Areas: Cancer, Neuroscience, Signal transduction
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-10000, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: Q12866,Q06418
Gene ID: 10461/7301
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide from human protein
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 110kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Endoplasmic reticulum,endoplasmic reticulum membrane,Nucleus,nuclear envelope,nucleus,Plasma Membrane,integral component of plasma membrane

Product Link: https://www.elabscience.com/p-phospho_mertk_tyro3_(tyr753_tyr685)_polyclonal_antibody-42110.html
Manaul Link: https://www.elabscience.com/viewpdf-42110-elabscience-E-AB-51041.PDF