Phospho-PRC1 (Thr481) Polyclonal AntibodyE-AB-51047
Product Category: Phospho/Acetyl/Methyl
Description: This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated witHuman, Mouseitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.
Research Areas: Cancer, Cell Biology
Size: 200 uL
Recommended Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Gene ID: 9055
Immunogen: Synthetic Phospho peptide from human protein
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Affinity purification
Observed MW: 72kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus. Cytoplasm. Cytoplasm>cytoskeleton>spindle pole. Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis.
Product Link: https://www.elabscience.com/p-phospho_prc1_(thr481)_polyclonal_antibody-42246.html
Manaul Link: https://www.elabscience.com/viewpdf-42246-elabscience-E-AB-51047.PDF