Mouse Monoclonal Antibody to S100A1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2C8B8;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of S100A1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=133
Reference: 1. Koenig A, Wojcieszyn J, Weeks BR, et al. Vet Pathol. 2001;38(4):427-35. ; 2. Hoyaux D, Decaestecker C, Heizmann CW, et al. Brain Res. 2000;867(1-2):280-8. ; 3. Pingerelli PL, Mizukami H, Wagner AS, et al. J Protein Chem. 1990;9(2):169-75. ;

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