Mouse Monoclonal Antibody to FMR1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4G9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human FMR1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 71kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=308
Reference: 1. BMC Mol Biol. 2008 Oct 15;9:89. ; 2. Fertil Steril. 2008 Oct 28.

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