Mouse Monoclonal Antibody to RUNX1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5A1;
Isotype: Mouse IgG1
Immunogen: Synthesized peptide of human RUNX1. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 55kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=570
Reference: 1. J Cell Physiol. 2009 Feb;218(2):343-9. ; 2. J Radiat Res (Tokyo). 2008 Sep;49(5):549-55.

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