Mouse Monoclonal Antibody to IL2RA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. ; ; ; ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Monkey; Rat
Clone: 1B5D12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human IL2RA (AA: 34-139) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 30.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3483
Reference: 1. Ann Hematol. 2012 Oct;91(10):1597-602. ; 2. Transplant Proc. 2012 May;44(4):1139-42. ;

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