Mouse Monoclonal Antibody to MAP3K7

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3E8H4;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human MAP3K7 (AA: 471-579) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
MW: 67.2kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3726
Reference: Asian Pac J Cancer Prev. 2013;14(1):315-20. ; Blood. 2012 Jul 12;120(2):347-55.;

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