Mouse Monoclonal Antibody to CBX3

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6D1C4;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CBX3 (AA: 1-183) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 20.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3972
Reference: 1.BMC Cancer. 2013 Mar 23;13:148. ; 2.PLoS One. 2012;7(8):e41401.;

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