Mouse Monoclonal Antibody to DDX5

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Monkey
Clone: 4F1C12;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human DDX5 (AA: 475-614) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 69.1kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4136
Reference: 1.Cancer Discov. 2012 Sep;2(9):812-25. ; 2.Nucleic Acids Res. 2012 Apr;40(7):3159-71.;

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