Mouse Monoclonal Antibody to DNMT3A

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4G5F11;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 102kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4166
Reference: 1.PLoS One. 2014 Jun 17;9(6):e93353. ; 2.Asian Pac J Cancer Prev. 2013;14(10):5713-8.;

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