Mouse Monoclonal Antibody to TRIM25

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/50 - 1/250; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5B5B12;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human TRIM25 (AA: 211-360) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 68.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4228
Reference: 1.Science. 2015 Oct 9;350(6257):217-21. ; 2.Oncogene. 2015 Nov 12;34(46):5729-38.;

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