Mouse Monoclonal Antibody to BRD2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1H6B12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human BRD2 (AA: 227-364) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 24.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4302
Reference: 1.Mol Biol Cell. 2013 Nov;24(22):3557-68. ; 2.J Biol Chem. 2010 Mar 5;285(10):7610-8.;

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