Mouse Monoclonal Antibody to ATP2A1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: N/A; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human;Mouse;Monkey
Clone: 4F11F6
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ATP2A1 (AA: 487-631) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 110kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4360
Reference: 1.Biochem Biophys Res Commun. 2012 Jun 29;423(2):212-7.2.Mol Genet Metab. 2013 Sep-Oct;110(1-2):162-9.

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