Anti-CD57 Monoclonal Antibody
Anti-CD57 Monoclonal Antibody

Anti-CD57 Monoclonal Antibody

IHC539-100

Regular price $50.00 You Pay

Supplier:  GenomeMe

Description:

Cluster of differentiation 57 (CD57), also known as NK-1, is an antigen detectable in natural killer cells, some T-lymphocytes and normal peripheral blood mononuclear cells, myeloid cells, and a variety of polypeptides, lipids, and chondroitin sulfate proteoglycans. CD57 is indicated as a marker for tumors of neuroendocrine origin, including pheochromocytomas, paragangliomas, carcinoid tumor, and medulloblastomas, as well as various neural tumors including neuromas, neurofibromas, schwannomas, and granular cell tumors. CD57 is also detectable in ganglioneuroma and prostate carcinoma. Anti-CD57 is used to distinguish nodular lymphocyte-predominant Hodgkin’s lymphoma from T-cell/histiocyte-rich large B-cell lymphoma, nodular sclerosis Hodgkin’s disease, and follicular lymphoma.

Specifications:

Clone IHC539
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200
  1. Lanier LL, et al. J Immunol. 1983; 131:1789-96.
  2. Ritchie AW, et al. Clin Exp Immunol. 1983; 51:439-47.
  3. Caillaud JM, et al. Cancer Res. 1984; 44:4432-9.
  4. Tucker, et al. Cell Differ. 1984; 14:223-30.
  5. Abo T, et al. Cell Immunol. 1982; 73:376-84.
  6. Khoury T, et al. Int J Exp Pathol. 2011; 92:87-96.
  7. Boudova L, et al. Blood. 2003; 102:3753-8.
  8. Dabbs DJ. 2014: 324.
  9. Eiden SV, et al. Hum Pathol. 2002; 33:1126-32.