BOLL Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Areas: Epigenetics and Nuclear Signaling
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:25-1:50
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: Q8N9W6
Gene Accession: BC033674
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human BOLL
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Testis specific. Not expressed in early embryos, primordial germ cells and spermatogonial cells. First expressed in the cytoplasm of spermatocytes and then persists through meiosis.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-boll_polyclonal_antibody-30082.html
Manual Link: https://www.elabscience.com/viewpdf-30082-elabscience-E-AB-10022.PDF