FBXW7 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.
Research Areas: Cancer, Cell Biology
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:100-1:300
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q969H0
Gene Accession: BC117244
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human FBXW7
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Isoform 1 is widely expressed. Isoform 4 is expressed in brain.
Cellular Localization: Cytoplasm; Nucleus; Nucleus>nucleolus and Nucleus>nucleoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-fbxw7_polyclonal_antibody-31105.html
Manual Link: https://www.elabscience.com/viewpdf-31105-elabscience-E-AB-11064.PDF