NDUFA13 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300
Size: 200 uL
Concentration: 0.7mg/mL
Swissprot: Q9P0J0
Gene Accession: BC009189
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human NDUFA13
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 17kDa
Tissue Specificity/Positive Control: Widely expressed, with highest expression in heart, skeletal muscle, liver, kidney and placenta. In intestinal mucosa, down-regulated in areas involved in Crohn disease and ulcerative colitis.
Cellular Localization: Mitochondrion inner membrane. Nucleus. May be translocated into the nucleus upon IFN/RA treatment.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-ndufa13_polyclonal_antibody-31323.html
Manual Link: https://www.elabscience.com/viewpdf-31323-elabscience-E-AB-11283.PDF