Histone H3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: WB,IF
Recommended Dilutions: WB 1:500-1:1000, IHC 1:50-100, IF/ICC 1:100-1:200
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P68431
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human HIST1H3D (Ab-10)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 15kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus. Chromosome.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-histone_h3_polyclonal_antibody-39918.html
Manual Link: https://www.elabscience.com/viewpdf-39918-elabscience-E-AB-12077.PDF