EIF2 alpha Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: WB,IHC,IF
Recommended Dilutions: WB 1:500-1:1000, IHC 1:50-100, IF/ICC 1:100-1:200
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P05198
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human EIF2S1 (Ab-51)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 36kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasmic granule. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity).
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-eif2_alpha_polyclonal_antibody-39947.html
Manual Link: https://www.elabscience.com/viewpdf-39947-elabscience-E-AB-12106.PDF