Gabra3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. GABRA3 (Gamma-Aminobutyric Acid Type A Receptor Alpha3 Subunit) is a Protein Coding gene. Diseases associated with GABRA3 include Thyrotoxic Periodic Paralysis and Mucopolysaccharidosis Ii. Among its related pathways are Ligand-gated ion channel transport and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include chloride channel activity and GABA-A receptor activity. An important paralog of this gene is GABRA1.
Research Areas:
Applications: WB
Recommended Dilutions: WB 1:500-1:1000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P20236
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of Rat Gabra3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 55kDa
Tissue Specificity/Positive Control:
Cellular Localization: Plasma Membrane,postsynaptic membrane,Other locations:cell junction,chloride channel complex,GABA-A receptor complex
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-gabra3_polyclonal_antibody-39967.html
Manual Link: https://www.elabscience.com/viewpdf-39967-elabscience-E-AB-12126.PDF