GAS6 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Research Areas: Cancer, Cardiovascular, Signal transduction, Stem cells
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:10-1:50
Size: 200 uL
Concentration: 0.2mg/mL
Swissprot: Q14393
Gene Accession: NP_000811
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human GAS6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-gas6_polyclonal_antibody-31913.html
Manual Link: https://www.elabscience.com/viewpdf-31913-elabscience-E-AB-12462.PDF