ACIN1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Concentration: 0.2mg/mL
Swissprot: Q9UKV3
Gene Accession: NP_001158286
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human ACIN1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Ubiquitous.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-acin1_polyclonal_antibody-32379.html
Manual Link: https://www.elabscience.com/viewpdf-32379-elabscience-E-AB-12937.PDF