Phospho-BAD (Ser112) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Research Areas: Cancer, Cell Biology, Metabolism
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Clonality: Polyclonal
Clone No:
SwissProt: Q92934
Gene ID: 572
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Bad around the phosphorylation site of Ser112
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW:
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Mitochondrion outer membrane. Cytoplasm. Upon phosphorylation, locates to the cytoplasm.

Product Link: https://www.elabscience.com/p-phospho_bad_(ser112)_polyclonal_antibody-25407.html
Manaul Link: https://www.elabscience.com/viewpdf-25407-elabscience-E-AB-20818.PDF