Phospho-c-Fos (Ser362) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: P01100
Gene ID: 2353
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human c-Fos around the phosphorylation site of Ser362
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 40kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus.

Product Link: https://www.elabscience.com/p-phospho_c_fos_(ser362)_polyclonal_antibody-25752.html
Manaul Link: https://www.elabscience.com/viewpdf-25752-elabscience-E-AB-21163.PDF