Anti-Mouse CD126 (IL-6R) Monoclonal Antibody (FITC conjugated)

Supplier: Elabscience
Product Type: monoclonal antibody for FC
Description: CD126 is an 80 kD IL-6 receptor ? chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on activated T and B cells, monocytes, hepatocytes, and plasma cells. High affinity IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor ? chain (CD130 or gp130). CD126 binds IL-6 with low affinity, but does not signal. The ? chain (gp130, CD130) does not bind IL-6 by itself, but associates with the ?-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation. The D7715A7 (15A7) antibody blocks IL-6/IL-6 receptor interactions.
Resarch Areas: Immunology, Stem cells
Size: 500 ug
Clonality: Monoclonal
Clone No: 15A7
Swissprot: P22272
Applications: FCM
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ? 1.0 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2b
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Purification:
Conjugation: FITC
Storage: Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

Product Link: https://www.elabscience.com/p-anti_mouse_cd126_(il_6r)_monoclonal_antibody_(fitc_conjugated)-39383.html
Manual Link: https://www.elabscience.com/viewpdf-39383-elabscience-E-AB-2132.PDF