VGF Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.VGF (VGF Nerve Growth Factor Inducible) is a Protein Coding gene. Diseases associated with VGF include Pulmonary Large Cell Neuroendocrine Carcinoma and Pheochromocytoma. GO annotations related to this gene include growth factor activity and neuropeptide hormone activity.
Research Areas: Cancer, Neuroscience, Signal transduction
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: O15240
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human VGF.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 67kDa
Tissue Specificity/Positive Control: Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.
Cellular Localization: Secreted. Cytoplasmic vesicle>secretory vesicle. Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-vgf_polyclonal_antibody-29891.html
Manual Link: https://www.elabscience.com/viewpdf-29891-elabscience-E-AB-33566.PDF