MGMT Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: WB
Recommended Dilutions: WB 1:500-1:1000
Size: 200 uL
Concentration: 2mg/mL
Swissprot: P16455
Gene Accession:
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant human Methylated DNA protein cysteine methyltransferase protein
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 22 kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-mgmt_polyclonal_antibody-40701.html
Manual Link: https://www.elabscience.com/viewpdf-40701-elabscience-E-AB-40155.PDF