ABCB7 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 
Research Areas: Metabolism, Signal transduction, Stem cells
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:25-100, ELISA 1:2000-5000
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: O75027
Gene Accession: BC006323
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Fusion protein of human ABCB7
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control:
Cellular Localization: Mitochondrion inner membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-abcb7_polyclonal_antibody-36443.html
Manual Link: https://www.elabscience.com/viewpdf-36443-elabscience-E-AB-17048.PDF